The accident happend just after 7 o'clock Tuesday night at Kellogg and Webb.
Police were attempting to pull the driver over for speeding - when the cycle driver sped off. The officer caught up to them 1/4 to 1/2 mile later, where they had crashed.
A female rider was pronounced dead at the scene, a male rider was taken to an area hospital in serious condition. It was not immediately known who was driving the motorcycle.
Stay with KAKE and KAKE.com for the latest on this developing story.