C.J. Spiller scored twice and had 123 yards rushing in sparking the Buffalo Bills' 35-17 rout over the Kansas City Chiefs on Sunday.
Ryan Fitzpatrick threw two touchdown passes, including a 49-yarder to Stevie Johnson, and Leodis McKelvin scored on an 88-yard punt return -- the second longest in team history -- in the Bills' home opener.
Buffalo's high-priced defense had five sacks and forced three turnovers as the Bills bounced back from a dreadful season-opening 48-28 loss at the New York Jets last week.
Dwayne Bowe scored both touchdowns for Kansas City, both coming in the final seven minutes to make the score respectable. Coming off a 40-24 loss at Atlanta, the Chiefs opened a season 0-2 for the sixth time in seven years.