The Houston Texans bounced back from their lone loss of the season by trouncing the only other AFC team with a winning record heading into Week 7.
The Texans improve to 6-1 by blasting Baltimore 43-13, dropping the Ravens to 5-2. It is Houston first victory over Baltimore in seven meetings.
Matt Schaub threw two touchdown passes and Arian Foster ran for two scores for the Texans, whose defense bounced back big time from an embarrassing loss to Green Bay. Antonio Smith had two sacks and J.J. Watt deflected a pass that Johnathan Joseph intercepted and returned 52 yards to pay dirt.
Baltimore quarterback Joe Flacco threw two interceptions and was sacked four times.
But there was an encouraging sign for the Ravens. Terrell Suggs, the 2011 defensive player of the year, had a sack and three tackles in his first action since undergoing surgery on his right Achilles tendon last May.
The NFC East-leading Giants overcame a late go-ahead touchdown by the Redskins and beat visiting Washington 27-23.
Eli Manning connected with Victor Cruz on a 77-yard TD pass two plays and 19 seconds after Redskins rookie quarterback Robert Griffin III capped a potential game-winning, 77-yard drive with a 30-yard touchdown pass to Santana Moss.
Griffin had Washington moving for another score when Moss fumbled as he was being tackled by Chase Blackburn after an 11-yard reception. Giants rookie Jayron Hosley recovered at the Washington 43 to seal New York's fifth win in seven games. The division-rival Redskins fall to 3-4.
At Foxborough, Stephen Gostkowski drilled a 48-yard field goal at 3:58 of overtime before Mark Sanchez fumbled with 7:28 left on the clock to secure the Patriots' 29-36 win over the New York Jets.
Gostkowski also hit a 43-yard field goal at the end of regulation after the Patriots blew a 10-point lead in the fourth quarter.
Tom Brady was 26 of 42 for 259 yards and two touchdowns as the Patriots took over the AFC East lead at 4-3. Sanchez completed 28 of his 41 passes for 341 yards and a TD for the 3-4 Jets.
There was also overtime in Oakland as Sebastien Janikowski hit a 40-yard field goal at 2:02 of the extra session to give the Raiders a 26-23 triumph over Jacksonville. The game-winning boot came after Cecil Shorts lost a fumble to set up the Raiders deep in Jacksonville territory.
Carson Palmer passed for 298 yards and a touchdown for the Raiders, who trailed 20-6 in the third quarter before winning for the second time in six games. Palmer also ran for the game-tying touchdown with 3:38 remaining in the fourth quarter.
The Jaguars dropped to 1-5.
Drew Brees threw for 377 yards and four touchdowns to lead New Orleans to a 35-28 come-from-behind road victory over the Tampa Bay Buccaneers. He extends his NFL record for consecutive games with a TD pass to 49. Brees led long scoring drives on four straight possessions to turn a 14-point deficit into a 28-21 halftime lead.
Linebacker Jonathan Vilma played for the first time while appealing a season-long suspension for his role in the Saints bounty program.
The Saints defense turned back two drives near the end zone in the second half, including the final three plays of the game to preserve New Orleans' second straight win following an 0-4 start.
Buccaneers quarterback Josh Freeman threw for 420 yards and three touchdowns but his bid to force overtime ended with three straight incompletions from inside the Saints' 10. The Bucs fall to 2-4.
After opening the season 4-0 the Arizona Cardinals sit 4-3 following a 21-14 loss at Minnesota. Adrian Peterson ran for 153 yards and a first-quarter touchdown, and the Vikings survive an ugly second half to run their record to 5-2.
Rookie Harrison Smith returned an interception 31 yards for a touchdown in the first minute of the second half, giving the Vikings enough of a cushion to withstand a lack of offense down the stretch.
Minnesota survives an up-and-down outing by Christian Ponder, who threw a TD pass to Percy Harvin but also threw an interception that led to a second-quarter touchdown run by LaRod Stephens-Howling. Ponder has seven turnovers in the last three games; two of them were turned into touchdowns last week at Washington.
Arizona quarterback John Skelton went 25 for 36 for 262 yards and two turnovers.
The Colts surpassed last year's win total in game six of the 2012 season.
Indianapolis improves to 3-3 with a 17-13 victory over visiting Cleveland.
The player Indy picked No. 1 after finishing 2-14 helped in a big way. Andrew Luck became the first Colts quarterback to rush for two touchdowns in a game since 1988, scoring on runs of 3 and 5 yards in the first half.
Adam Vinatieri (vin-uh-TEHR'-ee) added a 38-yard field goal for Indy.
Browns rookie QB Brandon Weeden threw for 247 yards and two touchdowns, but couldn't prevent Cleveland from losing its 11th straight road game and falling to 1-5.
The Green Bay Packers defeated the St. Louis Rams 30-20 for their first two-game winning streak of the season.
Aaron Rodgers completed 30 of 37 passes for 342 yards and three touchdowns to help the Pack get to 4-3 on the season.
Randall Cobb caught two of Rogers TD tosses and teammate Jordy Nelson had eight receptions for a season-best 122 yards.
The Rams first home loss of the season leaves them with a 3-4 record.
Dan Bailey's right foot lifted the Dallas Cowboys to a 19-14 victory at Carolina.
Bailey's 28-yarder with 3:25 left in the game gave the Cowboys the lead. He capped the scoring with 53 seconds left on the clock, kicking his fourth field goal of the game.
Tony Romo led a 10-play, 44-yard drive to set up the winning score. He threw for 227 yards and a TD on the day.
The Cowboys' ninth straight regular season victory over the Panthers gets them to 3-3. Carolina dips to 1-5.
Matt Hasselbeck engineered the 22nd fourth-quarter comeback of his NFL career and second in as many weeks, lifting the Tennessee Titans to a 35-34 win over Buffalo on the Bills' home field.
Hasselbeck's 15-yard scoring pass to Nate Washington with 1:03 on the clock was the game winner.
Jason McCourty's interception of a Ryan Fitzpatrick pass set up the decisive drive.
Fitzpatrick threw for three scores but also had two turnovers.
Tennessee got a long-awaited breakout performance from Chris Johnson. The veteran running back picked up 195 yards on the ground and scored two TDs. Jamie Harper also scored twice for the Titans, who are 3-4 on the season.